Mechanisims of asthma and allergic disease – 1083. CD23, Total IgE and Th1/Th2 cytokines in asthma patients
نویسنده
چکیده
Results Serum sCD23 mean±SE was significantly increased (p<0.05) in asthma (581.16 ± 35.72 pg/mL), when compared to controls (429.49 ± 31.29 pg/mL). Similarly serum IgE mean±SE (154.03 ± 33.24) and blood histamine (46.7 ± 7.23) levels were increased significantly (P<0.01) in patients with asthma; while IFN-g, a Th1 cytokine, was significantly lower (P<0.05) in asthma (3.28 ± 0.65) than in controls (9.45 ± 1.58). Pearson’s correlation coefficient showed a significant (P<0.05, r=0.50) association between sCD23, IL-5 with serum IgE concentration, however, IFNg was not correlated with IgE. Serum IL-4 and CD23 in buccal mucosa and stool samples were below detectable levels.
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